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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRN2
All Species:
13.33
Human Site:
T840
Identified Species:
20.95
UniProt:
Q9H0D6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0D6
NP_036387.2
950
108582
T840
N
A
A
P
P
P
V
T
Y
Q
G
N
L
Y
R
Chimpanzee
Pan troglodytes
XP_514546
950
108522
T840
N
A
A
P
P
P
A
T
Y
Q
G
N
L
Y
R
Rhesus Macaque
Macaca mulatta
XP_001094734
961
109718
T851
N
A
A
P
P
P
A
T
Y
Q
G
N
L
Y
R
Dog
Lupus familis
XP_534324
950
108331
T840
N
A
A
P
P
P
A
T
Y
Q
G
N
L
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBR1
951
108669
N840
N
T
A
L
P
P
A
N
Y
Q
G
N
N
Y
R
Rat
Rattus norvegicus
NP_001102066
561
63850
K468
R
G
Q
A
Q
I
P
K
L
M
S
N
M
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505862
950
108030
G840
S
N
A
A
P
P
G
G
Y
Q
G
H
F
S
R
Chicken
Gallus gallus
Q5ZIP4
949
108524
A840
A
N
A
V
P
L
G
A
Y
G
S
P
Y
T
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM71
908
103942
G811
G
G
G
G
G
G
Y
G
Q
G
G
G
Y
G
Q
Honey Bee
Apis mellifera
XP_392371
860
99367
S763
K
F
R
D
P
K
Y
S
S
N
F
I
F
P
A
Nematode Worm
Caenorhab. elegans
Q9U299
975
110109
R867
R
G
N
S
Y
D
D
R
R
G
G
G
G
G
G
Sea Urchin
Strong. purpuratus
XP_795068
1073
120270
P907
S
S
Q
S
H
F
L
P
S
A
Y
A
M
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FQ03
1020
116807
Q903
Y
V
P
P
I
P
Y
Q
H
G
G
Y
M
A
P
Baker's Yeast
Sacchar. cerevisiae
Q02792
1006
115915
G907
K
Q
N
I
V
P
V
G
P
K
G
I
T
Q
Y
Red Bread Mold
Neurospora crassa
Q8WZX5
1072
118291
G925
G
Y
G
G
N
G
G
G
Y
Q
A
N
G
G
G
Conservation
Percent
Protein Identity:
100
99.7
97.6
98
N.A.
96
56.2
N.A.
91.1
82.9
N.A.
N.A.
N.A.
51.2
54
50.5
52.5
Protein Similarity:
100
99.8
98
99
N.A.
97
57.6
N.A.
95.4
90.5
N.A.
N.A.
N.A.
63.2
66.5
63.7
63.4
P-Site Identity:
100
93.3
93.3
93.3
N.A.
66.6
6.6
N.A.
46.6
26.6
N.A.
N.A.
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
66.6
13.3
N.A.
60
26.6
N.A.
N.A.
N.A.
13.3
13.3
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.6
40.5
40.8
Protein Similarity:
N.A.
N.A.
N.A.
58
57.4
56.1
P-Site Identity:
N.A.
N.A.
N.A.
20
20
20
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
27
47
14
0
0
27
7
0
7
7
7
0
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
7
7
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
7
0
0
0
7
0
0
0
0
7
0
14
0
0
% F
% Gly:
14
20
14
14
7
14
20
27
0
27
67
14
14
20
14
% G
% His:
0
0
0
0
7
0
0
0
7
0
0
7
0
0
0
% H
% Ile:
0
0
0
7
7
7
0
0
0
0
0
14
0
0
0
% I
% Lys:
14
0
0
0
0
7
0
7
0
7
0
0
0
0
0
% K
% Leu:
0
0
0
7
0
7
7
0
7
0
0
0
27
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
20
0
0
% M
% Asn:
34
14
14
0
7
0
0
7
0
7
0
47
7
0
0
% N
% Pro:
0
0
7
34
54
54
7
7
7
0
0
7
0
14
14
% P
% Gln:
0
7
14
0
7
0
0
7
7
47
0
0
0
7
7
% Q
% Arg:
14
0
7
0
0
0
0
7
7
0
0
0
0
7
47
% R
% Ser:
14
7
0
14
0
0
0
7
14
0
14
0
0
7
0
% S
% Thr:
0
7
0
0
0
0
0
27
0
0
0
0
7
7
0
% T
% Val:
0
7
0
7
7
0
14
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
7
0
20
0
54
0
7
7
14
34
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _